SYSTEMIC AND LOCALIZED SCLERODERMA

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Diagnosis and treatment of systemic and localized scleroderma

Department of Clinical Immunology and Rheumatology, Sahara Hospital, Lucknow, India, 226010 [email protected] Scleroderma or progressive systemic sclerosis is diagnosed clinically by typical features of skin thickening, Raynaud’s phenomenon and visceral organ involvement, and serologically by distinct autoantibody subsets. These differentiate the disease into the ‘limited’ and ‘diffuse’ vari...

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Localized Scleroderma

Morphea (localized scleroderma) is an autoimmune disease characterized by sclerosis of the skin and, in some cases, subcutaneous tissue. It occurs in children and adults. It is distinct from systemic sclerosis, but may nevertheless be associated with significant functional and cosmetic impairment. Morphea has several distinct subtypes, including circumscribed, linear, and generalized, all of wh...

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Antiphospholipid Antibodies and Systemic Scleroderma

OBJECTIVE Antiphospholipid antibodies (APLs) could be associated with an increased risk of vascular pathologies in systemic scleroderma. The aim of our study was to search for APLs in patients affected by systemic scleroderma and to evaluate their involvement in the clinical manifestations of this disease. MATERIALS AND METHODS We conducted a cross-sectional descriptive study, from January 20...

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Mycophenolate mofetil for localized scleroderma

Commentary Systemic sclerosis is one of the rheumatic diseases that is associated with the worst prognosis. Systemic sclerosis is divided into localized and systemic forms. Localized scleroderma comprises four subtypes, namely morphea, generalized morphea, linear scleroderma and en coup de saber, and is more commonly encountered in children. Although conversion into systemic sclerosis is very u...

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Antiphospholipid Antibodies and Systemic Scleroderma

Dear Editor: We read with great interest the article by Touré and colleagues published in a recent issue of your journal, entitled " Antiphospholipid Antibodies and Systemic Scleroderma ". In this study, they investigated 40 patients with systemic scleroderma (SSc) for the presence of antiphospholipid antibodies (aPLs). Overall, they found aPLs in 23 (57.5%) patients. The most frequently encoun...

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ژورنال

عنوان ژورنال: ??????? ?????????. ????????????? ?????

سال: 2022

ISSN: ['2500-3410']

DOI: https://doi.org/10.17513/srbs.1271